Relative Costs of Surgical and Transcatheter Aortic Valve Replacement and Medical Therapy

Circ Cardiovasc Interv. 2020 May;13(5):e008681. doi: 10.1161/CIRCINTERVENTIONS.119.008681. Epub 2020 May 14.

Abstract

Background: The number of patients treated for aortic valve disease in the United States is increasing rapidly. Transcatheter aortic valve replacement (TAVR) is supplanting surgical aortic valve replacement (SAVR) and medical therapy (MT). The economic implications of these trends are unknown. Therefore, we undertook to determine the costs, inpatient days, and number of admissions associated with treating aortic valve disease with SAVR, TAVR, or MT.

Methods: Using the Nationwide Readmissions Database, we identified patients with aortic valve disease admitted 2012 to 2016 for SAVR, TAVR, and disease symptoms (congestive heart failure, unstable angina, non-ST-elevation myocardial infarction, syncope). Patients not undergoing SAVR or TAVR were classified as receiving MT. Beginning with the index admission, we estimated inpatient costs, days, and admissions over 6 months.

Results: Among 190 563 patients with aortic valve disease, the average aggregate 6-month inpatient costs were $59 743 for SAVR, $64 395 for TAVR, and $23 460 for MT. Mean index admission was longer for SAVR (10.0 days) than for TAVR (7.0 day) or MT (5.3 days), but the average number of unplanned readmission inpatient days was 2.0 for SAVR, 3.0 for TAVR, and 4.3 for MT; the average number of total admissions was 1.3 for SAVR, 1.5 for TAVR, and 1.7 for MT (P<0.01 for all). TAVR index admission costs decreased over time to become similar to SAVR costs by 2016.

Conclusions: Aggregate costs were higher for TAVR than SAVR and were significantly more expensive than MT alone. However, TAVR costs decreased over time while SAVR and MT costs remained unchanged.

Keywords: aortic valve; heart failure; myocardial infarction; syncope; transcatheter aortic valve replacement.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cardiovascular Agents / adverse effects
  • Cardiovascular Agents / economics*
  • Cardiovascular Agents / therapeutic use*
  • Cost-Benefit Analysis
  • Databases, Factual
  • Drug Costs*
  • Female
  • Heart Valve Diseases / economics*
  • Heart Valve Diseases / therapy*
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / economics*
  • Hospital Costs*
  • Humans
  • Length of Stay / economics
  • Male
  • Middle Aged
  • Patient Readmission / economics
  • Time Factors
  • Transcatheter Aortic Valve Replacement / adverse effects
  • Transcatheter Aortic Valve Replacement / economics*
  • Treatment Outcome
  • United States

Substances

  • Cardiovascular Agents