Diffuse alveolar hemorrhage secondary to plastic fume exposure: A case report

Monaldi Arch Chest Dis. 2020 Jul 22;90(3). doi: 10.4081/monaldi.2020.1304.

Abstract

A 31-year non-smoker man, working in plastic making industry for 12 years presented with cough and streaking hemoptysis for 2 days. Computed tomography (CT) of chest showed patchy ground glass opacities with interlobular septal thickening in bilateral lung parenchyma. Fiber optic bronchoscopy (FOB) was done. Sequential lavage was taken which showed progressively increasing hemorrhagic fluid. His diffusion capacity for carbon monoxide (DLCO) was 38.08 mL/mmHg/Mi (126%) predicted on day 2 of admission, 32.36 ml/mmHg/Mi (106%) predicted on discharge and 39.63 mL/mmHg/Mi (130%) predicted on going back to work. He was diagnosed with plastic fume exposure related pulmonary alveolar hemorrhage.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bronchoscopy / methods
  • Carbon Monoxide / analysis
  • Cough / diagnosis
  • Cough / etiology
  • Hemoptysis / chemically induced
  • Hemoptysis / diagnosis
  • Hemorrhage / chemically induced*
  • Hemorrhage / diagnosis
  • Humans
  • Lung Diseases / chemically induced
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / pathology*
  • Lung Diseases / physiopathology
  • Male
  • Occupational Diseases / chemically induced*
  • Occupational Diseases / prevention & control
  • Occupational Exposure / adverse effects*
  • Occupational Exposure / prevention & control
  • Plastics / adverse effects*
  • Pulmonary Alveoli / blood supply
  • Pulmonary Alveoli / pathology
  • Pulmonary Diffusing Capacity / physiology
  • Tomography, X-Ray Computed / methods

Substances

  • Plastics
  • Carbon Monoxide