The influence of a dentifrice containing a zinc salt and a nonionic antimicrobial agent on the maintenance of gingival health

J Clin Periodontol. 1987 Sep;14(8):457-61. doi: 10.1111/j.1600-051x.1987.tb02251.x.

Abstract

The purpose of the present investigation was to test the concept that a dentifrice containing zinc citrate and Triclosan could maintain gingival health. The gingival health of 101 young predominately female student nurses in Oslo was brought to a high level by professional cleaning supported by oral hygiene instruction. The criterion of gingival health was less than or equal to 5 elicited bleeding sites from a full mouth assessment. The mean bleeding value attained for the whole group was 3.5. 2 balanced groups were formed, based on the initial number of elicited bleeding sites and plaque values. One group used the test dentifrice and the other group the placebo for 6 months, with an intermediate assessment after 3 months. The placebo group failed to maintain the standard of oral hygiene and gingival health that had been achieved by professional care. In contrast, the group using the test dentifrice for 6 months exhibited similar levels of plaque and gingival health to that observed at baseline following oral hygiene instruction. After 6 months, less than 7% of the subjects in the placebo group possessed healthy gingivae in contrast to 60% of the test group. Thus a dentifrice containing a zinc salt and nonionic germicide had successfully maintained gingival health in a group of young adults.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Citrates / therapeutic use*
  • Citric Acid
  • Clinical Trials as Topic
  • Dental Plaque Index
  • Dentifrices / therapeutic use*
  • Double-Blind Method
  • Female
  • Gingivitis / prevention & control*
  • Humans
  • Male
  • Oral Hygiene
  • Phenyl Ethers / therapeutic use*
  • Toothpastes / therapeutic use*
  • Triclosan / therapeutic use*

Substances

  • Citrates
  • Dentifrices
  • Phenyl Ethers
  • Toothpastes
  • Citric Acid
  • Triclosan