A Rare, Unreported Cognitive Side Effect of Topiramate: Do We Know It All Yet?

Cureus. 2020 Nov 5;12(11):e11342. doi: 10.7759/cureus.11342.

Abstract

This report describes a unique, dose dependent side effect of a commonly used drug, topiramate. Although cognitive side effects of this drug have previously been reported in literature, we present a case of drug-induced amnesia, with support from Naranjo Nomogram, as a hitherto unreported side effect of topiramate. Here, we highlight the importance of being cognizant of such rare cognitive side effects, with the aim of improving patient outcome by timely recognition, and discontinuation of the offending drug, as the side effect was fortunately found to be reversible.

Keywords: cognitive side effects; naranjo algorithm; serotonin; substance induced dissociative amnesia; topiramate.

Publication types

  • Case Reports