Aneurysmal subarachnoid hemorrhage during pregnancy: a comprehensive and systematic review of the literature

Neurosurg Rev. 2021 Oct;44(5):2511-2522. doi: 10.1007/s10143-020-01457-2. Epub 2021 Jan 7.

Abstract

Aneurysmal subarachnoid hemorrhage (aSAH) is an emergent condition requiring rapid intervention and prolonged monitoring. There are few recommendations regarding the management of aSAH in pregnancy. We identified all available literature and compiled management decisions as well as reported outcomes through a systematic literature review without meta-analysis to provide recommendations for management of aSAH during pregnancy. We included a total of 23 articles containing 54 cases of pregnancy-related aSAH in our review. From these reports and other literature, we evaluated information on aSAH pathophysiology, diagnosis, and management with respect to pregnancy. Early transfer to an appropriate facility with neurocritical care, a high-risk obstetric service, and a neurosurgery team available is crucial for the management of aSAH in pregnancy. Intensive monitoring and a multidisciplinary approach remain fundamental to ensure maternal and fetal health.

Keywords: Pregnancy; Subarachnoid hemorrhage; Vasospasm.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Female
  • Humans
  • Neurosurgical Procedures
  • Pregnancy
  • Subarachnoid Hemorrhage* / diagnosis
  • Subarachnoid Hemorrhage* / etiology
  • Subarachnoid Hemorrhage* / surgery
  • Vasospasm, Intracranial*