Detection of the germline KIT S476I mutation in a kindred with familial mastocytosis associated with gastrointestinal stromal tumors

Affiliations

• ¹ Department of Dermatology, University of Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
• ² Gemeinschaftspraxis für Humangenetik und Genetische Labore, Hamburg, Germany.
• ³ Diagnostic Hematology, Department of Laboratory Medicine, University Hospital Basel and University Basel, Basel, Switzerland.
• ⁴ Department of Gastroenterology and Hepatology, University Hospital of Cologne, Cologne, Germany.
• ⁵ Department of General, Visceral and Tumor Surgery, University of Cologne, Cologne, Germany.
• ⁶ Institute for Pathology, University of Cologne, Cologne, Germany.
• ⁷ Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany.
• ⁸ Department I of Internal Medicine, Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf, University of Cologne, Cologne, Germany; Center for Molecular Medicine, University of Cologne, Cologne, Germany.
• ⁹ Division of Allergy, Department of Dermatology, University Hospital Basel and University of Basel, Basel, Switzerland; Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland.
• ¹⁰ Department of Dermatology, University of Cologne, Cologne, Germany. Electronic address: iliana.tantcheva-poor@uk-koeln.de.