Toxic erythema of chemotherapy affecting the ears of an infant: A case report

Pediatr Dermatol. 2021 Mar;38(2):512-513. doi: 10.1111/pde.14522. Epub 2021 Jan 22.

Abstract

A 15-month-old boy presented with new onset symmetric erythema of the conchal bowls bilaterally in the setting of treatment with cytarabine. Findings were consistent with a diagnosis of toxic erythema of chemotherapy, an adverse effect of chemotherapy. In this report, we detail this uncommon manifestation in a young child along with a brief literature review of the background, pathophysiology, and treatment strategies of toxic erythema of chemotherapy to increase awareness of this presentation in pediatric populations.

Keywords: Ara-c ears; toxic erythema of chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Cytarabine* / adverse effects
  • Erythema* / chemically induced
  • Humans
  • Infant
  • Male

Substances

  • Cytarabine