Pseudohyperkalemia and Pseudohyponatremia in Two Children with T-Cell Acute Lymphoblastic Leukemia

Zelda Ghersin; Neil D Fernandes; Amanda Winkler; Phoebe Yager

doi:10.1016/j.jpeds.2021.01.044

Pseudohyperkalemia and Pseudohyponatremia in Two Children with T-Cell Acute Lymphoblastic Leukemia

J Pediatr. 2021 May:232:294-298. doi: 10.1016/j.jpeds.2021.01.044. Epub 2021 Jan 22.

Authors

Zelda Ghersin¹, Neil D Fernandes¹, Amanda Winkler¹, Phoebe Yager²

Affiliations

¹ Department of Pediatrics, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA.
² Department of Pediatrics, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA. Electronic address: pyager@mgh.harvard.edu.

PMID: 33493492
DOI: 10.1016/j.jpeds.2021.01.044

Abstract

Pseudohyperkalemia and pseudohyponatremia are phenomena in which hematologic disorders with high cell counts result in factitious electrolyte measurements that can result in inappropriate treatment. We describe 2 children with leukemia presenting with both disturbances to highlight the importance of correlating electrolyte results from plasma with those from whole blood before intervening.

Keywords: ISE; electrolytes; leukemia; pediatric; pseudohyperkalemia; pseudohyponatremia.

Publication types

Case Reports

MeSH terms

Child
Humans
Hyperkalemia / diagnosis
Hyperkalemia / etiology*
Hyponatremia / diagnosis
Hyponatremia / etiology*
Infant
Male
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / complications
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*