Low CtBP2 expression is associated with a stem cell-like signature and adverse clinical outcome in childhood B-cell lymphoblastic leukemia

Leukemia. 2021 Sep;35(9):2684-2687. doi: 10.1038/s41375-021-01151-2. Epub 2021 Feb 12.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Alcohol Oxidoreductases / metabolism*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Biomarkers, Tumor / metabolism*
  • Child
  • Child, Preschool
  • Co-Repressor Proteins / metabolism*
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Male
  • Neoplastic Stem Cells / drug effects
  • Neoplastic Stem Cells / metabolism
  • Neoplastic Stem Cells / pathology*
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / metabolism
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / mortality*
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Prognosis
  • Survival Rate
  • Young Adult

Substances

  • Biomarkers, Tumor
  • Co-Repressor Proteins
  • Alcohol Oxidoreductases
  • CTBP2 protein, human