Genome-wide association study of metabolites in patients with coronary artery disease identified novel metabolite quantitative trait loci

Zixian Wang; Qian Zhu; Yibin Liu; Shiyu Chen; Ying Zhang; Qilin Ma; Xiaoping Chen; Chen Liu; Heping Lei; Hui Chen; Jing Wang; Shufen Zheng; Zehua Li; Lingjuan Xiong; Weihua Lai; Shilong Zhong

doi:10.1002/ctm2.290

Genome-wide association study of metabolites in patients with coronary artery disease identified novel metabolite quantitative trait loci

Clin Transl Med. 2021 Feb;11(2):e290. doi: 10.1002/ctm2.290.

Authors

Zixian Wang^{1

2

3}, Qian Zhu^{1

2

4}, Yibin Liu^{1

2}, Shiyu Chen^{1

2

3}, Ying Zhang⁵, Qilin Ma⁶, Xiaoping Chen⁷, Chen Liu⁸, Heping Lei², Hui Chen^{1

2}, Jing Wang^{1

2

3}, Shufen Zheng⁴, Zehua Li¹, Lingjuan Xiong¹, Weihua Lai¹, Shilong Zhong^{1

2

3

4

5}

Affiliations

¹ Department of Pharmacy, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
² Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
³ School of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
⁴ School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.
⁵ Department of Cardiology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
⁶ Department of Cardiology, Xiangya Hospital, Central South University, Changsha, China.
⁷ Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
⁸ Department of Cardiology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

China
Cohort Studies
Coronary Artery Disease / genetics*
Female
Genetic Predisposition to Disease / genetics*
Genome-Wide Association Study / methods*
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide / genetics
Quantitative Trait Loci / genetics*