Ophthalmic associations of oculodermal melanocytosis in a tertiary eye hospital in South Asia

Ther Adv Ophthalmol. 2021 Feb 14:13:2515841421993539. doi: 10.1177/2515841421993539. eCollection 2021 Jan-Dec.

Abstract

Oculodermal melanocytosis (ODM), though rare, is associated with a number of sight-threatening complications including glaucoma. The purpose of this Case Series study was to determine the ophthalmic features in patients diagnosed with ODM. Here, we describe five patients presented with ODM, with the most common ocular features identified being hyperpigmentation of the conjunctiva, sclera and heterochromia iridis. Others included hyperpigmentation of trabecular meshwork, glaucoma, cataract, retinal detachment and ocular hypertension in one patient. As such, all patients with ODM should have a comprehensive ocular evaluation.

Keywords: glaucoma; hyperpigmentation; oculodermal melanocytosis; ophthalmic features.