Cranioplasty Using Customized 3-Dimensional-Printed Titanium Implants: An International Collaboration Effort to Improve Neurosurgical Care

World Neurosurg. 2021 May:149:174-180. doi: 10.1016/j.wneu.2021.02.104. Epub 2021 Feb 27.

Abstract

Background: Evolutions in cranioplasty have allowed for the creation of customized implants via advances in 3-dimensional (3D) printing technology, although the high cost associated with this technique presents a barrier for low-income countries. Through an international collaboration, our team in Da Nang, Vietnam is able to create low-cost, customized titanium implants for patients with skull defects. We discuss the details of our collaboration and present our experience with this procedure.

Methods: We conducted a retrospective review of 35 patients who underwent cranioplasty using custom-made titanium implants. The molding and implant making processes were performed by our neurosurgeons using a 3D printer donated by the United Kingdom-based nongovernmental organization Facing the World. We obtained demographic and preoperative data (reason for skull defect, location, surface area measurement of defect) and postoperative data (complications, cosmetic outcome, and patient satisfaction).

Results: The median patient age was 27 years (range, 16-60 years). Primary indications for craniectomy included traumatic brain injury from motor vehicle accident (77.1%), cerebrovascular disease (11.4%), implant failure following previous cranioplasty (5.7%), and fall (5.7%). Postoperatively, all implants were found to have an excellent fit; at 6-month follow-up, none of the implants required removal. Complications included 4 postoperative hematomas and 1 surgical site infection. All the patients had improved aesthetic appearance and high satisfaction.

Conclusions: Cranioplasty using customized titanium implants yields excellent results for patients with skull defects, demonstrating the practicality of this technique for cranioplasty in low-income countries. Our experience highlights the importance of ongoing international collaboration to improve neurosurgical care in these countries.

Keywords: 3D printing; Cranioplasty; Global neurosurgery; International collaboration.

MeSH terms

  • Adolescent
  • Adult
  • Brain Injuries, Traumatic / epidemiology
  • Brain Injuries, Traumatic / surgery
  • Cerebrovascular Disorders / epidemiology
  • Cerebrovascular Disorders / surgery
  • Craniotomy / methods*
  • Female
  • Humans
  • Internationality
  • Intersectoral Collaboration*
  • Male
  • Middle Aged
  • Neurosurgical Procedures / instrumentation
  • Neurosurgical Procedures / methods*
  • Plastic Surgery Procedures / instrumentation
  • Plastic Surgery Procedures / methods*
  • Printing, Three-Dimensional*
  • Prosthesis Implantation / instrumentation
  • Prosthesis Implantation / methods
  • Retrospective Studies
  • Titanium*
  • Vietnam / epidemiology
  • Young Adult

Substances

  • Titanium