Tissue effects of a newly developed diode pumped pulsed Thulium:YAG laser compared to continuous wave Thulium:YAG and pulsed Holmium:YAG laser

World J Urol. 2021 Sep;39(9):3503-3508. doi: 10.1007/s00345-021-03634-4. Epub 2021 Mar 16.

Abstract

Purpose: The objective of this study is to evaluate the laser-tissue effects of laser radiation emitted by a newly developed high frequency pulsed Tm:YAG laser in comparison to the continuous wave Tm:YAG laser and the pulsed Ho:YAG laser.

Methods: Ex-vivo experiments were performed on freshly slaughtered porcine kidneys in a physiological saline solution. Experiments were performed using two different laser devices in different settings: A Tm:YAG laser was operated in a pulsed mode up to 300 Hz and in a continuous wave (CW) mode. Results were compared with a 100 W standard pulsed Ho:YAG laser system. Comparative tissue experiments were performed at 5 W, 40 W and 80 W. The incision depth and the laser damage zone were measured under a microscope using a calibrated ocular scale.

Results: Increased laser power resulted in increased incision depth and increased laser damage zone for all investigated lasers in this set-up. The Ho:YAG created the largest combined tissue effect at the 5 W power setting and seems to be the least controllable laser at low power for soft tissue incisions. The CW Tm:YAG did not incise at all at 5 W, but created the largest laser damage zone. For the new pulsed Tm:YAG laser the tissue effect grew evenly with increasing power.

Conclusion: Among the investigated laser systems in this setting the pulsed Tm:YAG laser shows the most controllable behavior, insofar as both the incision depth and the laser damage zone increase evenly with increasing laser power.

Keywords: Continuous wave Thulium:YAG laser (CW); Holmium:YAG laser; Pulsed Thulium:YAG laser; Tissue interaction.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Humans
  • In Vitro Techniques
  • Kidney / surgery*
  • Laser Therapy / methods
  • Lasers, Solid-State / therapeutic use*
  • Swine
  • Thulium

Substances

  • Thulium