A Unique Case of Spontaneous Pneumomediastinum in a Patient With COVID-19 and Influenza Coinfection

J Investig Med High Impact Case Rep. 2021 Jan-Dec:9:23247096211016228. doi: 10.1177/23247096211016228.

Abstract

Spontaneous pneumomediastinum is reported in patients with coronavirus disease-2019 (COVID-19) and influenza infection independently, usually associated with noninvasive and mechanical ventilation. We report a case of spontaneous pneumomediastinum in a patient with COVID-19 and influenza coinfection. A 58-year-old male admitted with shortness of breath, diagnosed with COVID-19 and influenza infection. A computed tomography angiogram showed pneumomediastinum. He was treated conservatively with 15 L of oxygen, remdesivir, convalescent plasma, and oseltamivir. The case is being reported for its uniqueness since this is the first documented case of spontaneous pneumomediastinum in COVID-19 and influenza coinfection.

Keywords: COVID-19; influenza; pneumomediastinum.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use
  • COVID-19 / complications*
  • COVID-19 / diagnosis
  • COVID-19 / therapy
  • COVID-19 Serotherapy
  • Coinfection
  • Combined Modality Therapy
  • Drug Therapy, Combination
  • Humans
  • Immunization, Passive
  • Influenza, Human / complications*
  • Influenza, Human / diagnosis
  • Influenza, Human / therapy
  • Male
  • Mediastinal Emphysema / diagnostic imaging
  • Mediastinal Emphysema / therapy
  • Mediastinal Emphysema / virology*
  • Middle Aged
  • Oxygen Inhalation Therapy
  • Pneumonia, Viral / complications*
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / therapy
  • SARS-CoV-2

Substances

  • Antiviral Agents