Background: Primary cardiac lymphoma (PCL) is rare and can present with a wide variety of clinical symptoms, frequently leading to a delay in diagnosis.
Case summary: We report a case of a PCL in an 81-year-old man. Cardiac magnetic resonance imaging showed multiple masses in the right atrium and a mass in the right ventricular outflow tract extending to the pulmonary artery. Biopsy revealed a diffuse large B-cell lymphoma. The patient also had metastases to the liver and lung on the positron emission tomography-computed tomography (PET-CT) scan. He was treated with R-CHOP chemotherapy, with complete remission documented PET-CT scans.
Conclusion: Although most patients with PCL die before chemotherapy can be initiated, a timely diagnosis can result in a favourable outcome.
Keywords: Cardiac MRI; Cardiac lymphoma; Echocardiography; Primary cardiac tumour.
© The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.