Colorectal polyp characterization with endocytoscopy: Ready for widespread implementation with artificial intelligence?

Best Pract Res Clin Gastroenterol. 2021 Jun-Aug:52-53:101721. doi: 10.1016/j.bpg.2020.101721. Epub 2020 Dec 18.

Abstract

Endocytoscopy provides an in-vivo visualization of nuclei and micro-vessels at the cellular level in real-time, facilitating so-called "optical biopsy" or "virtual histology" of colorectal polyps/neoplasms. This functionality is enabled by 520-fold magnification power with endocytoscopy and recent breakthroughs in artificial intelligence (AI) allowing a great advance in endocytoscopic imaging; interpretation of images is now fully supported by AI tool which outputs predictions of polyp histopathology during colonoscopy. The advantage of the use of AI during optical biopsy can be appreciated especially by non-expert endoscopists who to increase performance. This paper provides an overview of the latest evidence on colorectal polyp characterization with endocytoscopy combined with AI and identify the barriers to its widespread implementation.

Keywords: Artificial intelligence (AI); Computer aided diagnosis; Endocytoscopy; Optical diagnosis.

Publication types

  • Review

MeSH terms

  • Artificial Intelligence / standards*
  • Colonic Polyps / pathology*
  • Colonoscopy / methods*
  • Colorectal Neoplasms / pathology*
  • Endoscopy / methods*
  • Humans