Establishing core domain sets for Chronic Nonbacterial Osteomyelitis (CNO) and Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO): A report from the OMERACT 2020 special interest group

Melissa Oliver; Aruni Jayatilleke; Eveline Wu; Farzana Nuruzzaman; Cassyanne Aguiar; Aleksander Lenert; Micol Romano; Gabriele Simonini; Samir Shah; Matthew Hollander; Alhanouf Alsaleem; Emily Fox; Alexander Theos; Athimalaipet V Ramanan; Anja Schnabel; Sivia Lapidus; Lori Tucker; Karen Onel; Seza Ozen; Fatma Dedeoglu; Polly J Ferguson; Beverley Shea; Jonathan Akikusa; Christian Hedrich; Philip Mease; Yongdong Zhao

doi:10.1016/j.semarthrit.2021.05.015

Establishing core domain sets for Chronic Nonbacterial Osteomyelitis (CNO) and Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO): A report from the OMERACT 2020 special interest group

Semin Arthritis Rheum. 2021 Aug;51(4):957-961. doi: 10.1016/j.semarthrit.2021.05.015. Epub 2021 Jun 7.

Authors

Melissa Oliver¹, Aruni Jayatilleke², Eveline Wu³, Farzana Nuruzzaman⁴, Cassyanne Aguiar⁵, Aleksander Lenert⁶, Micol Romano⁷, Gabriele Simonini⁸, Samir Shah⁹, Matthew Hollander¹⁰, Alhanouf Alsaleem¹¹, Emily Fox¹², Alexander Theos¹³, Athimalaipet V Ramanan¹⁴, Anja Schnabel¹⁵, Sivia Lapidus¹⁶, Lori Tucker¹⁷, Karen Onel¹⁸, Seza Ozen¹⁹, Fatma Dedeoglu²⁰, Polly J Ferguson²¹, Beverley Shea²², Jonathan Akikusa²³, Christian Hedrich²⁴, Philip Mease²⁵, Yongdong Zhao²⁶

Affiliations

¹ Division of Pediatric Rheumatology, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: msoliver@iu.edu.
² Rheumatology, Department of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.
³ Division of Pediatric Rheumatology, Department of Pediatrics, The University of North Carolina, Chapel Hill, NC, USA.
⁴ Division of Pediatric Rheumatology, Department of Pediatrics, Renaissance School of Medicine at Stony Brook University, Stony Brook Children's Hospital, Stony Brook, NY, USA.
⁵ Division of Pediatric Rheumatology, Department of Pediatrics, Children's Hospital of The King's Daughters, Eastern Virginia Medical School, Norfolk, VA, USA.
⁶ Division of Immunology, Department of Internal Medicine, University of Iowa Hospitals & Clinics, Iowa City, IA, USA.
⁷ Division of Rheumatology, ASST Gaetano Pini, Milan, Italy; Division of Paediatric Rheumatology, Department of Paediatrics, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada.
⁸ Rheumatology Unit, Meyer Children Hospital, University of Florence, Florence, Italy.
⁹ Division of Rheumatology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts, USA.
¹⁰ Pediatric Rheumatology, University of Vermont Medical Center, Burlington, VT, USA.
¹¹ Departments of Pediatric Rheumatology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
¹² Pediatric Rheumatology, Children's Mercy Hospital, Kansas City, Missouri, USA.
¹³ CRMO Patient/parent Partner; Department of Human Science, Georgetown University, Washington, DC, USA.
¹⁴ Department of Paediatric Rheumatology, University Hospitals Bristol NHS Foundation Trust and Translational Health Sciences, University of Bristol, Bristol, UK.
¹⁵ Pediatric Rheumatology and Immunology, Department of Pediatrics, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
¹⁶ Division of Pediatric Rheumatology, Department of Pediatrics, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center and Hackensack Meridian School of Medicine, Hackensack, New Jersey, USA.
¹⁷ Division of Rheumatology, Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
¹⁸ Division of Pediatric Rheumatology, Hospital for Special Surgery, NY, NY, USA.
¹⁹ Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University, Ankara, Turkey.
²⁰ Division of Immunology, Rheumatology Program, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
²¹ Stead Family Department of Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
²² Division of Rheumatology, Department of Medicine, Ottawa hospital Research Institute, School of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
²³ Rheumatology Service Department of General Medicine Royal Children's Hospital, Melbourne, Australia.
²⁴ Department of Women's & Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK; Department of Pediatric Rheumatology, Alder Hey Children's NHS Foundation Trust Hospital, Liverpool, UK.
²⁵ Department of Rheumatology, Swedish Medical Center, Providence St Joseph Health and University of Washington, Seattle, WA, USA.
²⁶ Pediatric Rheumatology, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.

PMID: 34176644
DOI: 10.1016/j.semarthrit.2021.05.015

Abstract

Objective: A working group was established to develop a core domain set (CDS) for Chronic Nonbacterial Osteomyelitis (CNO) and Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO) following the OMERACT filter 2.1.

Methods: A scoping review to identify disease-related manifestations was performed, followed by a special interest group (SIG) session at OMERACT2020 to begin the CNO/SAPHO CDS framework.

Results: Candidate items were identified from the scoping review and most fell under Life Impact and Pathophysiology Manifestation core areas. A SIG agreed on the need to develop a CDS for CNO and SAPHO (100%) and for children and adults (91%).

Conclusion: Based on candidate items identified, qualitative research and Delphi surveys will be performed as next steps.

Keywords: Acne; Chronic nonbacterial osteomyelitis; Hyperostosis; OMERACT; Osteitis; Outcome research; Pustulosis; Synovitis.

Publication types

Review

MeSH terms

Acne Vulgaris*
Acquired Hyperostosis Syndrome* / diagnosis
Adult
Child
Humans
Hyperostosis*
Osteitis*
Osteomyelitis* / diagnosis
Public Opinion
Synovitis*