Trends in office visits and treatment for urticaria in children in the United States, 1998-2016

Pediatr Dermatol. 2021 Sep;38(5):1162-1168. doi: 10.1111/pde.14726. Epub 2021 Aug 2.

Abstract

Background/objectives: Urticaria is a common condition with an estimated prevalence of up to 23% in the pediatric population. Studies characterizing visits and treatments for urticaria in the pediatric population are unavailable. Understanding visit and treatment trends for urticaria in the pediatric population may help inform care for patients with urticaria.

Methods: A total of 108 278 outpatient records from the National Ambulatory Medical Care Survey representing 3.4 billion visits by patients of age 18 and younger were analyzed. This study included the calendar years 1998 through 2016.

Results: Pediatricians saw the largest proportion of all visits (52.7%). Male and female patients accounted for approximately equal proportions of all visits for urticaria. There was a slight male predominance in visits to pediatricians (53.7%), whereas dermatologists saw female patients more frequently (63.3%). Most visits for urticaria were by non-Hispanic (78.1%) and White (78.2%) patients. H1 antihistamines were the most commonly prescribed treatment (70.3%), whereas topical corticosteroids were prescribed least frequently (4.9%). Topical corticosteroids were most frequently prescribed by dermatologists (7.7%). Non-H1 antihistamine and non-corticosteroid therapy were prescribed in 9.7% of all visits and in 4.5% of visits to pediatricians. Most visits for urticaria were to physicians in metropolitan areas (88.8%). Pediatricians saw the highest number of non-metropolitan area visits (56.3%).

Conclusions: H1 antihistamines were the most commonly used therapy (70%), consistent with established treatment guidelines. Male and female pediatric patients present equally often for urticaria, but sex differences were seen with visit frequencies to certain specialties.

Keywords: NAMCS; United States; antihistamine; corticosteroid; pediatrics; urticaria; visits.

MeSH terms

  • Adolescent
  • Ambulatory Care
  • Child
  • Female
  • Health Care Surveys
  • Histamine H1 Antagonists / therapeutic use
  • Humans
  • Male
  • Office Visits*
  • United States / epidemiology
  • Urticaria* / drug therapy
  • Urticaria* / epidemiology

Substances

  • Histamine H1 Antagonists