Scrub typhus meningoencephalitis presenting as opsoclonus myoclonus syndrome: A video-based case

Trop Doct. 2022 Jan;52(1):192-195. doi: 10.1177/00494755211034381. Epub 2021 Aug 6.

Abstract

Opsoclonus myoclonus syndrome secondary to scrub typhus infection is a rare clinical entity. Hence, it is important to know its clinical manifestations and complications, so that it can be properly managed. We report a 28-year-old female whose initial manifestation was only fever, which subsided in four days. Two days later, she developed opsoclonus myoclonus syndrome. This was managed with doxycycline and clonazepam, but as it persisted, intravenous immunoglobulin was added. She showed excellent response to treatment.

Keywords: Scrub typhus; immunoglobulin; myoclonus; opsoclonus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Doxycycline / therapeutic use
  • Female
  • Fever / drug therapy
  • Humans
  • Meningoencephalitis* / complications
  • Meningoencephalitis* / drug therapy
  • Opsoclonus-Myoclonus Syndrome* / diagnosis
  • Opsoclonus-Myoclonus Syndrome* / drug therapy
  • Opsoclonus-Myoclonus Syndrome* / etiology
  • Scrub Typhus* / complications
  • Scrub Typhus* / diagnosis
  • Scrub Typhus* / drug therapy

Substances

  • Doxycycline