1 Harefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
2 Harefield Pulmonary Rehabilitation Unit, Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
3 Contributed equally.
4 Harefield Respiratory Research Group, Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK r.barker2@rbht.nhs.uk.
5 National Heart & Lung Institute, Imperial College, London, UK.
6 Dept of Respiratory Medicine, The Hillingdon Hospital NHS Trust, London, UK.
7 Dept of Medical Statistics, Research & Development, Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
8 Dept of Respiratory Medicine, Royal Brompton & Harefield Hospitals, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
9 Dept of Occupational and Environmental Medicine, Imperial College, London, London, UK.