Reference management softwares are a powerful tool in the researchers' armamentarium. They primarily help in re-sequencing, re-styling and reformatting of the citation content in the research manuscripts. They also enable multi-user collaboration on research and allow the researcher to manage database searches and digital libraries. Using these softwares allows synchronization of cloud based digital libraries on multiple electronic devices enabling remote access, and also allows for management of online portfolios. We, herein, describe the basic principles, functions, and limitations of various reference management softwares.