Making Lemonade: Putting the Wisdom of the Genome to Work in Atopic Dermatitis

Zhaolin Zhang; James T Elder

doi:10.1016/j.jid.2021.05.027

Making Lemonade: Putting the Wisdom of the Genome to Work in Atopic Dermatitis

J Invest Dermatol. 2021 Nov;141(11):2561-2564. doi: 10.1016/j.jid.2021.05.027.

Authors

Zhaolin Zhang¹, James T Elder²

Affiliations

¹ Department of Dermatology, University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan, USA.
² Department of Dermatology, University of Michigan Medical School, University of Michigan, Ann Arbor, Michigan, USA; Ann Arbor VA Medical Center, Ann Arbor, Michigan, USA. Electronic address: jelder@umich.edu.

Abstract

Getting from a GWAS hit to an actionable gene remains a challenge in complex disease genetics. In a new article of the Journal of Investigative Dermatology, Sobczyk et al. (2021) use a wide variety of genomic data to generate a prioritization algorithm to tackle this problem in atopic dermatitis, calling on the wisdom of the genome to generate promising results.

Making Lemonade: Putting the Wisdom of the Genome to Work in Atopic Dermatitis

Authors

Affiliations

Abstract

Publication types

MeSH terms

Grants and funding