Whole Blood Transfusion: Past, Present, and Future

Elizabeth A Godbey

doi:10.1016/j.cll.2021.07.008

Whole Blood Transfusion: Past, Present, and Future

Clin Lab Med. 2021 Dec;41(4):659-667. doi: 10.1016/j.cll.2021.07.008. Epub 2021 Sep 29.

Author

Elizabeth A Godbey¹

Affiliation

¹ Department of Pathology, Virginia Commonwealth University Health, Richmond, VA, USA. Electronic address: Elizabeth.Godbey@vcuhealth.org.

PMID: 34689972
DOI: 10.1016/j.cll.2021.07.008

Abstract

Transfusion of whole blood largely was replaced by component therapy in the 1970s and 1980s. The recent military operations in Iraq and Afghanistan returned whole blood to military trauma care. Eventually, whole blood use was incorporated into some civilian trauma care. It has been utilized in several other civilian populations as well. Trials to compare whole blood to component therapy are ongoing.

Keywords: Cold-stored whole blood; Fresh whole blood; Low-titer group O whole blood; Whole blood.

Publication types

Review

MeSH terms

Blood Transfusion*
Humans
Wounds and Injuries*