Cervical Myelopathy: Diagnosis, Contemporary Treatment, and Outcomes

Am J Med. 2022 Apr;135(4):435-443. doi: 10.1016/j.amjmed.2021.11.007. Epub 2021 Nov 30.

Abstract

Cervical myelopathy is a clinical syndrome caused by compression of the spinal cord between the levels of the C1 and T1 vertebrae. Its clinical presentation can mimic other degenerative and neurological pathologies, making diagnosis challenging. Diagnosis is confirmed with appropriate imaging studies carefully correlated with history and physical examination. Treatment options are focused on decompression of the spinal canal from an anterior, posterior, or combined anterior and posterior surgical approach depending on the location of compression and patient factors. Outcomes are favorable if treatment is performed prior to severe symptom onset.

Keywords: Cervical disc arthroplasty; Cervical myelopathy; Fusion; Laminectomy; Laminoplasty; Spine surgery.

Publication types

  • Review

MeSH terms

  • Cervical Vertebrae / diagnostic imaging
  • Cervical Vertebrae / surgery
  • Decompression, Surgical / methods
  • Humans
  • Spinal Cord Diseases* / diagnosis
  • Spinal Cord Diseases* / surgery
  • Spinal Fusion*
  • Treatment Outcome