Comparison of First and Second Wave Cohorts of Multisystem Inflammatory Disease Syndrome IN Children

Pediatr Infect Dis J. 2022 Jan 1;41(1):e21-e25. doi: 10.1097/INF.0000000000003388.

Abstract

Comparing first and second wave MIS-C cohorts at our quaternary pediatric institution, second wave were older, presented more frequently with shortness of breath, higher maximum troponin and N-terminal BNP, and more frequently required advanced respiratory and inotropic support. Despite increased severity in the second cohort, both cohorts had similar rates of coronary artery abnormalities, systolic dysfunction, and length of stay.

Publication types

  • Comparative Study

MeSH terms

  • COVID-19 / complications*
  • COVID-19 / physiopathology
  • Coronary Artery Disease / pathology
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Length of Stay / statistics & numerical data
  • Male
  • Prospective Studies
  • SARS-CoV-2 / pathogenicity
  • Severity of Illness Index
  • Systemic Inflammatory Response Syndrome / physiopathology*

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related