Validation of International Classification of Diseases criteria to identify severe influenza hospitalizations

Influenza Other Respir Viruses. 2022 May;16(3):371-375. doi: 10.1111/irv.12931. Epub 2022 Jan 4.

Abstract

In this cohort study of hospitalized patients with linked medical record data, we developed International Classification of Diseases (ICD) criteria that accurately identified laboratory-confirmed, severe influenza hospitalizations (positive predictive value [PPV] 80%, 95% confidence interval [CI] 71-87%), which we validated through medical record documentation. These criteria identify patients with clinically important influenza illness outcomes to inform evaluation of preventive and therapeutic interventions and public health policy recommendations.

Keywords: International Classification of Diseases; hospitalization; medical record extraction; severe influenza; validation.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Cohort Studies
  • Hospitalization
  • Humans
  • Influenza, Human* / diagnosis
  • Influenza, Human* / epidemiology
  • Influenza, Human* / therapy
  • International Classification of Diseases*
  • Predictive Value of Tests