Coinfection With Chlamydial and Gonorrheal Infection Among US Adults With Early Syphilis

Sex Transm Dis. 2022 Aug 1;49(8):e87-e89. doi: 10.1097/OLQ.0000000000001605. Epub 2022 Jan 24.

Abstract

Among 865 adults with early syphilis considered for a multicenter treatment trial, 234 (27%) were excluded before enrollment because of bacterial sexually transmitted infection coinfection. Coinfection with Neisseria gonorrhoeae (29%), Chlamydia trachomatis (22%), or both (23%) was common. Study findings highlight the need for comprehensive bacterial sexually transmitted infection screening in patients with syphilis.

Trial registration: ClinicalTrials.gov NCT03637660.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Chlamydia Infections* / complications
  • Chlamydia Infections* / diagnosis
  • Chlamydia Infections* / epidemiology
  • Chlamydia trachomatis
  • Coinfection* / microbiology
  • Gonorrhea* / complications
  • Gonorrhea* / diagnosis
  • Gonorrhea* / drug therapy
  • Humans
  • Neisseria gonorrhoeae
  • Prevalence
  • Syphilis* / complications
  • Syphilis* / diagnosis
  • Syphilis* / drug therapy

Associated data

  • ClinicalTrials.gov/NCT03637660