Adequacy Rate of Magnesium Citrate Bowel Preparation in a Large Retrospective Cohort

R I Med J (2013). 2022 Mar 1;105(2):46-50.

Abstract

Introduction: Magnesium Citrate (MC) is not FDA approved as a colonoscopy preparation. Advantages include low cost, small volume and accessibility without prescription. We retrospectively evaluated bowel preparations used in a private gastroenterology practice. The sample size is the largest for any similar studies (n =19,173).

Methods: Electronic Medical Records were queried for colonoscopies between 2010-2016. Bowel preps, indications (screening vs. other) and preparation adequacy were all recorded. Adequacy rates were calculated and compared using generalized linear modeling. Data were analyzed using SAS.

Results: The most common prep used was MC 2 bottles; screening (n=6,064, with 98.94% adequacy) and non-screening (n=3,251, with 99.29% adequacy), followed by MC 3 bottles; screening (n=2,757 with 90.35% adequacy), and non-screening (n=1,925 with 92.92% adequacy).

Conclusion: MC bowel preparation is adequate, well tolerated, and inexpensive. In a large retrospective analysis, it compares favorably to other preparations.

Keywords: bowel preparations; colonoscopy; magnesium citrate.

MeSH terms

  • Cathartics* / therapeutic use
  • Citric Acid / therapeutic use
  • Humans
  • Organometallic Compounds* / therapeutic use
  • Retrospective Studies

Substances

  • Cathartics
  • Organometallic Compounds
  • Citric Acid
  • magnesium citrate