Transcriptomic data of MCF-7 breast cancer cells treated with G1, a G-protein coupled estrogen receptor (GPER) agonist

Uttariya Pal; Ankur Sahu; Pankaj Barah; Anil Mukund Limaye

doi:10.1016/j.dib.2022.107948

Transcriptomic data of MCF-7 breast cancer cells treated with G1, a G-protein coupled estrogen receptor (GPER) agonist

Data Brief. 2022 Feb 13:41:107948. doi: 10.1016/j.dib.2022.107948. eCollection 2022 Apr.

Authors

Uttariya Pal¹, Ankur Sahu², Pankaj Barah², Anil Mukund Limaye¹

Affiliations

¹ Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati - 781039, Assam, India.
² Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur 784028, Assam, India.

Abstract

Besides short-term non-genomic effects, the G-protein coupled estrogen receptor (GPER) also mediates long-term genomic effects of estrogen. The genomic effects of GPER activation are not completely understood. G1 is a selective GPER agonist, which is popularly used for addressing the effects of GPER activation. Here, we present transcriptomic (RNA-seq) data on MCF-7 cells treated with 100 nM, or 1 µM G1 for a period of 48 h. The data are available from GEO (accession number GSE188706).

Keywords: G1; GPER; MCF-7; RNA-seq.