SARS-CoV-2 seroprevalence rates of children seeking medical care in Louisiana during the state stay at home order

Monika L Dietrich; Elizabeth B Norton; Debra Elliott; Ashley R Smira; Ofek Raviv; Daniel J Sasson; Chandler H Monk; Madalyn L Michael; Nathaniel Rogers; Julie A Rouelle; Nell G Bond; Kéren Aime-Marcelin; Alisha Prystowsky; Rebecca Kemnitz; Arunava Sarma; Sarah Talia Himmelfarb; Neha Sharma; Addison E Stone; Randall Craver; Alyssa R Lindrose; Leslie A Smitley; Robert B Uddo; Leann Myers; Stacy S Drury; John S Schieffelin; James E Robinson; Kevin J Zwezdaryk

doi:10.1016/j.jcvp.2021.100047

SARS-CoV-2 seroprevalence rates of children seeking medical care in Louisiana during the state stay at home order

J Clin Virol Plus. 2021 Dec;1(4):100047. doi: 10.1016/j.jcvp.2021.100047. Epub 2021 Nov 14.

Authors

Monika L Dietrich¹, Elizabeth B Norton², Debra Elliott¹, Ashley R Smira¹, Ofek Raviv³, Daniel J Sasson³, Chandler H Monk², Madalyn L Michael², Nathaniel Rogers⁴, Julie A Rouelle¹, Nell G Bond¹, Kéren Aime-Marcelin¹, Alisha Prystowsky¹, Rebecca Kemnitz¹, Arunava Sarma¹, Sarah Talia Himmelfarb^{1

5}, Neha Sharma¹, Addison E Stone², Randall Craver^{6

7}, Alyssa R Lindrose⁸, Leslie A Smitley¹, Robert B Uddo⁶, Leann Myers⁹, Stacy S Drury^{1

8

6}, John S Schieffelin^{1

5}, James E Robinson¹, Kevin J Zwezdaryk²

Affiliations

¹ Department of Pediatrics, Tulane University, New Orleans, LA, USA.
² Department of Microbiology and Immunology, Tulane University, New Orleans, LA, USA.
³ Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
⁴ Tulane School of Medicine, Tulane University, New Orleans, LA, USA.
⁵ Department of Medicine, Tulane University, New Orleans, LA, USA.
⁶ Children's Hospital New Orleans, New Orleans, LA USA.
⁷ Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA USA.
⁸ Department of Psychiatry and Behavioral Sciences, Tulane University, LA USA.
⁹ Department of Biostatistics & Data Science, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA.

Abstract

Serologic testing of residual blood samples from 812 children from a hospital in New Orleans, LA, between March and May 2020, demonstrated a SARS-CoV-2 seroprevalence of 6.8% based on S and N protein IgG; Black and Hispanic children, and children living in zip codes with lower household incomes were over-represented.

Keywords: COVID-19; Children; ELISA, enzyme-linked immunosorbent assay; SARS-CoV-2; SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2; Seroprevalence.

Abstract

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