Contemporary Management of Primary Hyperparathyroidism

Surg Clin North Am. 2022 Apr;102(2):251-265. doi: 10.1016/j.suc.2021.12.009.

Abstract

Primary hyperparathyroidism can be asymptomatic or symptomatic, as well as classic, normocalcemic, or normohormonal. It is important to rule out other causes of hypercalcemia or hyperparathyroidism. Preoperative localization with imaging is necessary for a minimally invasive approach and can be helpful even if planning 4-gland exploration. There are a variety of intraoperative techniques that can assist with localization as well as confirming success. Standard of care remains surgical resection of affected glands. However, there are less invasive management strategies that can be considered for poor surgical candidates.

Keywords: Localization; Minimally invasive; Primary hyperparathyroidism.

Publication types

  • Review

MeSH terms

  • Diagnostic Imaging
  • Humans
  • Hyperparathyroidism, Primary* / diagnosis
  • Hyperparathyroidism, Primary* / surgery