The Karolinska KI/K COVID-19 Immune Atlas: An open resource for immunological research and educational purposes

Scand J Immunol. 2022 Jun 2;96(1):e13195. doi: 10.1111/sji.13195. Online ahead of print.

Abstract

The Karolinska KI/K COVID-19 Immune Atlas project was conceptualized in March 2020 as a part of the academic research response to the developing SARS-CoV-2 pandemic. The aim was to rapidly provide a curated dataset covering the acute immune response towards SARS-CoV-2 infection in humans, as it occurred during the first wave. The Immune Atlas was built as an open resource for broad research and educational purposes. It contains a presentation of the response evoked by different immune and inflammatory cells in defined naïve patient-groups as they presented with moderate and severe COVID-19 disease. The present Resource Article describes how the Karolinska KI/K COVID-19 Immune Atlas allow scientists, students, and other interested parties to freely explore the nature of the immune response towards human SARS-CoV-2 infection in an online setting.

Keywords: COVID-19; Karolinska KI/K COVID-19 Immune Atlas; SARS-CoV-2; biobank; immune atlas; immune response.