Evaluation and Management of Asthma and Chronic Obstructive Pulmonary Disease Exacerbation in the Emergency Department

Emerg Med Clin North Am. 2022 Aug;40(3):539-563. doi: 10.1016/j.emc.2022.05.007. Epub 2022 Jul 9.

Abstract

Obstructive lung disease includes asthma and chronic obstructive pulmonary disease (COPD). Exacerbation of asthma or COPD can result in significant morbidity and mortality, and emergency department (ED) care is often required. ED evaluation should assess risk factors for severe exacerbation and the patient's hemodynamic and respiratory status. Assessments including chest radiograph, point-of-care ultrasound, capnography, and electrocardiogram can assist. First-line treatments for acute exacerbation include bronchodilators and corticosteroids. Noninvasive ventilation, magnesium, ketamine, and epinephrine should be considered in those with severe exacerbation. Mechanical ventilation is challenging and should use an obstructive lung strategy with permissive hypercapnia.

Keywords: Acute exacerbation; Asthma; COPD; Obstructive lung disease; Pulmonary.

Publication types

  • Review

MeSH terms

  • Asthma* / diagnosis
  • Asthma* / therapy
  • Emergency Service, Hospital
  • Humans
  • Noninvasive Ventilation*
  • Pulmonary Disease, Chronic Obstructive* / diagnosis
  • Pulmonary Disease, Chronic Obstructive* / therapy
  • Retrospective Studies