Concordance of the filmarray blood culture identification panel 2 and classical microbiological methods in a bacteriemia diagnostic unit

Diagn Microbiol Infect Dis. 2022 Dec;104(4):115787. doi: 10.1016/j.diagmicrobio.2022.115787. Epub 2022 Aug 10.

Abstract

Our study evaluates the effectiveness of the FilmArray Blood Culture Identification Panel 2 in a rapid bacteremia diagnostic system, using bacteriological culture as a reference. A total of 2042 positive blood cultures were analyzed, the FilmArray was performed for 175. Concordance was higher in monomicrobial bacteremia (95%) than in polymicrobial bacteremia's (72.2%). For detecting bacterial resistance mechanisms, concordance was very high (100% for Gram-positive bacteria and 98.12% for Gram-negative). This methodology provides significant improvements in response time and is especially useful for the detection of monomicrobial bacteremia.

Keywords: Bacteremia; Blood culture; Fungemia; Rapid diagnostic; Resistance mechanisms.

MeSH terms

  • Bacteremia* / diagnosis
  • Bacteremia* / microbiology
  • Blood Culture*
  • Gram-Positive Bacteria
  • Humans
  • Microbiological Techniques / methods