1 Giselle Corbie and Krista M. Perreira are with the Center for Health Equity Research, Department of Social Medicine, University of North Carolina, Chapel Hill. Giselle Corbie is also a guest editor of this special issue. Emily M. D'Agostino is with the Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, and is also a guest editor of this special issue. Susan Knox, Lisa M. Wruck, and Michael Cohen-Wolkowiez are with the Duke Clinical Research Institute, Duke University School of Medicine. Michael Cohen-Wolkowiez is also a guest editor of this special issue. Al Richmond is with Community-Campus Partnerships for Health, Raleigh, NC. Christopher W. Woods is with the Hubert-Yeargan Center for Global Health, Duke University Department of Medicine, Duke University School of Medicine. Gaurav Dave is with the Division of General Medicine and Clinical Epidemiology, University of North Carolina, Chapel Hill. Keith Marsolo is with the Department of Population Health Sciences, Duke University School of Medicine. Warren A. Kibbe is with the Department of Biostatistics and Bioinformatics, Duke University School of Medicine, and is also a guest editor of this special issue.