Translational opportunities emerge from genetic influences on health

Jacklyn N Hellwege; Todd L Edwards

doi:10.1016/j.molmed.2022.10.006

Translational opportunities emerge from genetic influences on health

Trends Mol Med. 2022 Dec;28(12):1028-1029. doi: 10.1016/j.molmed.2022.10.006. Epub 2022 Nov 4.

Authors

Jacklyn N Hellwege¹, Todd L Edwards²

Affiliations

¹ Division of Genetic Medicine, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
² Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: todd.l.edwards@vumc.org.

PMID: 36344332
DOI: 10.1016/j.molmed.2022.10.006

Abstract

Jukarainen et al. provide a novel perspective on the interpretation of heritable risk factors and human health. This study provides opportunities to focus translational efforts, characterize genetic influences on disease disparities, and improve communication between clinicians and patients regarding genetic risks. We describe their approach and discuss its implications, utility, and limitations.

MeSH terms

Communication*
Humans
Risk Factors

Grants and funding

K12 HD043483/HD/NICHD NIH HHS/United States