Hypercalcaemia secondary to acute rhinovirus infection

BMJ Case Rep. 2022 Nov 30;15(11):e253846. doi: 10.1136/bcr-2022-253846.

Abstract

Hypercalcaemia-induced rhinovirus has only been reported in a single study in children. Here, we report a case of hypercalcaemia in an adult who tested positive for rhinovirus. This patient underwent an extensive evaluation of hypercalcaemia, and it was found to be mediated by an increase in 1,25 hydroxy-vitamin D that could not be attributed to a cause. Their hypercalcaemia responded to standard treatment with intravascular expansion, bisphosphonates and calcitonin. Serum 1,25 OH vitamin D levels returned to normal with recovery from rhinovirus infection.

Keywords: Calcium and bone; Infectious diseases; Metabolic disorders.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Calcium-Regulating Hormones and Agents
  • Child
  • Enterovirus Infections*
  • Humans
  • Hypercalcemia* / diagnosis
  • Hypercalcemia* / drug therapy
  • Hypercalcemia* / etiology
  • Rhinovirus
  • Vitamin D

Substances

  • Calcium-Regulating Hormones and Agents
  • Vitamin D