Longer physical exercise duration prevents abnormal fasting plasma glucose occurrences in the third trimester: Findings from a cohort of women with gestational diabetes mellitus in Shanghai

Rui Zhang; Xiangjin Gao; Ting Sun; Huan Li; Qing Yang; Bin Li; Dongshan Zhu; Ruiping Wang

doi:10.3389/fendo.2023.1054153

Longer physical exercise duration prevents abnormal fasting plasma glucose occurrences in the third trimester: Findings from a cohort of women with gestational diabetes mellitus in Shanghai

Front Endocrinol (Lausanne). 2023 Jan 24:14:1054153. doi: 10.3389/fendo.2023.1054153. eCollection 2023.

Authors

Rui Zhang¹, Xiangjin Gao², Ting Sun³, Huan Li³, Qing Yang³, Bin Li¹, Dongshan Zhu⁴, Ruiping Wang^{1

2}

Affiliations

¹ Shanghai Skin Disease Hospital, Tongji University, Shanghai, China.
² School of Public Health, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
³ Obstetrics Department, Songjiang Maternal and Child Health Hospital, Shanghai, China.
⁴ School of Public Health, Shandong University, Jinan, Shandong, China.

Abstract

Objective: This study aims to investigate the relationship between daily physical exercise (PE) duration and frequency of abnormal plasma glucose (PG) times both during fasting and 2 h after a standard diet in women with gestational diabetes mellitus (GDM).

Methods: We established a cohort involving 878 GDM women. GDM was confirmed by a diagnostic 75-g oral glucose tolerance test. Information was extracted from the delivery records and antenatal checkup forms. Physical exercise information was collected through a questionnaire.

Results: Over 80% of GDM women were under 35 years old. An abnormal fasting PG with ≥1 occurrence presented in 742/878 (84.51%), and the abnormal PG 2 h after standard diet with ≥1 occurrence presented in 634/878 (72.21%). Compared to GDM women with ≥4 occurrences of abnormal fasting PG, GDM women with 0 occurrences (odds ratio (OR) = 2.56), one occurrence (OR = 1.94), two occurrences (OR = 2.29), and three occurrences (OR = 2.16) had a higher proportion of PE duration being in the 45-60-min/day group than those in the <45-min/day group, and GDM women also had a higher proportion of PE during being in the 61-90- and >90-min/day group than those in the <45-min/day group. However, the duration of PE was not associated to the number of abnormal PG occurrences 2-h after the standard diet.

Conclusion: Moderate-intensity PE duration in GDM women was negatively associated with the number of abnormal fasting PG occurrences but not with the number of PG occurrences 2 h after the standard diet.

Keywords: 2-h plasma glucose; abnormal plasma glucose; fasting plasma glucose; gestational diabetes mellitus; physical exercise duration.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Blood Glucose
China / epidemiology
Diabetes, Gestational*
Exercise
Fasting
Female
Humans
Pregnancy
Pregnancy Trimester, Third

Substances

Blood Glucose

Grants and funding

This work was supported by grants from the Research Program of Shanghai Sports Bureau (20Q001); the Shanghai Talent Development Fund (2021073); the Intelligence Fund of Shanghai Skin Diseases Hospital (2021KYQD01); and the China Fund for Medical Equipment (IIT2022-01).