Optimising post-operative radiation therapy after oncoplastic and reconstructive procedures

Trine Tramm; Orit Kaidar-Person

doi:10.1016/j.breast.2023.03.013

Optimising post-operative radiation therapy after oncoplastic and reconstructive procedures

Breast. 2023 Jun:69:366-374. doi: 10.1016/j.breast.2023.03.013. Epub 2023 Mar 28.

Authors

Trine Tramm¹, Orit Kaidar-Person²

Affiliations

¹ Department of Pathology, Aarhus University Hospital, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
² Breast Cancer Radiation Therapy Unit, Sheba Medical Center, Ramat Gan, Israel; The Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel; GROW-School for Oncology and Reproductive (Maastro), Maastricht University, Maastricht, the Netherlands. Electronic address: Orit.KaidarPerson@sheba.health.gov.il.

Abstract

Surgical techniques for breast cancer have been refined over the past decades to deliver an aesthetic outcome as close as possible to the contralateral intact breast. Current surgery further allows excellent aesthetic outcome even in case of mastectomy, by performing skin sparing or nipple sparing mastectomy in combination with breast reconstruction. In this review we discuss how to optimise post-operative radiation therapy after oncoplastic and breast reconstructive procedures, including dose, fractionation, volumes, surgical margins, and boost application.

Keywords: Boost; Breast cancer; Mastectomy; Oncoplastic; Radiation; Reconstruction.

Publication types

Review

MeSH terms

Breast / surgery
Breast Neoplasms* / radiotherapy
Breast Neoplasms* / surgery
Female
Humans
Mammaplasty* / methods
Mastectomy / methods
Mastectomy, Subcutaneous*
Nipples / surgery