In Patients With Sepsis, Initial Lactate Clearance Is Confounded Highly by Comorbidities and Poorly Predicts Subsequent Lactate Trajectory

Affiliations

• ¹ School of Medicine, University of Michigan Medical School, Ann Arbor, MI.
• ² Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI.
• ³ Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI; Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI; Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI; Weil Institute for Critical Care Research & Innovation, Ann Arbor, MI.
• ⁴ Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI; Weil Institute for Critical Care Research & Innovation, Ann Arbor, MI; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI.
• ⁵ Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI; Medicine Service, Infectious Diseases Section, Veterans Affairs (VA) Ann Arbor Healthcare System, Ann Arbor, MI. Electronic address: rchander@med.umich.edu.