Recent Advances in Senolysis for Age-Related Diseases

Physiology (Bethesda). 2023 Sep 1;38(5):0. doi: 10.1152/physiol.00003.2023. Epub 2023 May 16.

Abstract

Cellular senescence plays a central role in aging and geriatric diseases. Senolysis is a promising new strategy that selectively kills and eliminates senescent cells to control aging. To date, various senolytic drugs have been discovered and shown efficacy. This review highlights how we can benefit from senolysis.

Keywords: aging; geriatric diseases; senescence.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aging*
  • Cellular Senescence*
  • Humans