Keloids and Hypertrophic Scars

Ariel Knowles; Donald A Glass 2nd

doi:10.1016/j.det.2023.02.010

Keloids and Hypertrophic Scars

Dermatol Clin. 2023 Jul;41(3):509-517. doi: 10.1016/j.det.2023.02.010. Epub 2023 Apr 4.

Authors

Ariel Knowles¹, Donald A Glass 2nd²

Affiliations

¹ Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9069, USA.
² Department of Dermatology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9069, USA; Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA. Electronic address: donald.glass@utsouthwestern.edu.

PMID: 37236718
DOI: 10.1016/j.det.2023.02.010

Abstract

Keloids are an exuberant response to skin wound healing in which abundant scar tissue grows beyond the boundaries of the inciting insult. Age, race, location, family history and personal history of keloids are relevant factors concerning the risk of developing keloids. Because keloids are prone to recurrence after surgical excision, post-operative management plays an important role in the treatment of keloids. There are many modalities that can be used to treat keloids or prevent their recurrence; a multimodal approach is often necessary in difficult cases.

Keywords: Fibroblast; Hypertrophic scar; Keloids; Scarring; Treatment.

Publication types

Review

MeSH terms

Cicatrix, Hypertrophic* / complications
Cicatrix, Hypertrophic* / therapy
Humans
Keloid* / pathology
Keloid* / surgery