Clinical Algorithms with Race: An Online Database

medRxiv [Preprint]. 2023 Jul 6:2023.07.04.23292231. doi: 10.1101/2023.07.04.23292231.

Abstract

Some clinical algorithms incorporate a person's race, ethnicity, or both as an input variable or predictor in determining diagnoses, prognoses, treatment plans, or risk assessments. Inappropriate use of race and ethnicity in clinical algorithms at the point of care may exacerbate health disparities and promote harmful practices of race-based medicine. This article describes a comprehensive search of online resources, the scientific literature, and the FDA Drug Label Information that uncovered 39 race-based risk calculators, six laboratory test results with race-based reference ranges, one race-based therapy recommendation, and 15 medications with race-based recommendations. These clinical algorithms based on race are freely accessible through an online database. This resource aims to raise awareness about the use of race-based clinical algorithms and track the progress made toward eradicating the inappropriate use of race. The database will be actively updated to include clinical algorithms based on race that were previously omitted, along with additional characteristics of these algorithms.

Keywords: clinical algorithms; database; ethnicity; race.

Publication types

  • Preprint