Dawn of development: Exploring early human embryogenesis using stem cells

Timothy Theodore Ka Ki Tam; Shao Xu; Pentao Liu; Alejandro De Los Angeles

doi:10.1016/j.stem.2023.07.009

Dawn of development: Exploring early human embryogenesis using stem cells

Cell Stem Cell. 2023 Aug 3;30(8):1006-1007. doi: 10.1016/j.stem.2023.07.009.

Authors

Timothy Theodore Ka Ki Tam¹, Shao Xu², Pentao Liu³, Alejandro De Los Angeles⁴

Affiliations

¹ School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
² Centre for Translational Stem Cell Biology, Science Park, Sha Tin, Hong Kong Special Administrative Region, China.
³ School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China; Centre for Translational Stem Cell Biology, Science Park, Sha Tin, Hong Kong Special Administrative Region, China.
⁴ Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: adelosan@mit.edu.

PMID: 37541206
DOI: 10.1016/j.stem.2023.07.009

Abstract

Exploring the early stages of human embryonic development poses significant difficulties owing to ethical and technical limitations. Two recent studies in Nature report the self-organization of human stem cells into 3D embryoids that model features of the early post-implantation stages of human development.¹^,².

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Embryo Implantation*
Embryo, Mammalian
Embryonic Development
Female
Humans
Pregnancy
Stem Cells*