Relationships Between Schistosoma mansoni Infection Intensity and Nutritional Status and Anemia Among Preschool-aged Children in Uganda

Susannah Colt; Cole D Miller; Andrew Edielu; Emily L Webb; Patrice A Mawa; Hannah W Wu; Racheal Nakyesige; Edridah Muheki; Narcis Kabatereine; Amaya L Bustinduy; Jennifer F Friedman

doi:10.1093/cid/ciad470

Relationships Between Schistosoma mansoni Infection Intensity and Nutritional Status and Anemia Among Preschool-aged Children in Uganda

Clin Infect Dis. 2024 Jan 25;78(1):90-93. doi: 10.1093/cid/ciad470.

Authors

Susannah Colt^{1

2}, Cole D Miller³, Andrew Edielu^{4

5}, Emily L Webb⁶, Patrice A Mawa^{4

7

8}, Hannah W Wu^{1

2}, Racheal Nakyesige⁴, Edridah Muheki⁹, Narcis Kabatereine⁹, Amaya L Bustinduy⁵, Jennifer F Friedman^{1

2}

Affiliations

¹ Center for International Health Research, Rhode Island Hospital, Providence, Rhode Island, USA.
² Department of Pediatrics, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
³ University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
⁴ Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda.
⁵ Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.
⁶ Medical Research Council International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine, London, United Kingdom.
⁷ Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
⁸ Department of Immunology, Uganda Virus Research Institute, Entebbe, Uganda.
⁹ Vector Control Division, Ministry of Health, Kampala, Uganda.

PMID: 37585653
PMCID: PMC10810701 (available on 2024-08-16)
DOI: 10.1093/cid/ciad470

Abstract

In a cross-sectional analysis of 354 Ugandan children (age 12-48 months) infected with Schistosoma mansoni, we assessed relationships between infection intensity and nutritional morbidities. Higher intensity was associated with an increased risk for anemia (RR = 1.05, 95% confidence interval [CI] 1.01-1.10) yet not associated with risk for underweight, stunting, or wasting.

Keywords: anemia; preschool-age children; schistosomiasis; stunting.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Anemia* / epidemiology
Anemia* / etiology
Animals
Child
Child, Preschool
Cross-Sectional Studies
Humans
Infant
Nutritional Status
Prevalence
Schistosoma mansoni
Schistosomiasis mansoni* / complications
Schistosomiasis mansoni* / epidemiology
Uganda / epidemiology

Abstract

Publication types

MeSH terms

Grants and funding