Cardiac Conduction System Pacing: A Comprehensive Update

Pugazhendhi Vijayaraman; Mihal G Chelu; Karol Curila; Gopi Dandamudi; Bengt Herweg; Shumpei Mori; Marek Jastrzebski; Parikshit S Sharma; Kalyanam Shivkumar; Roderick Tung; Gaurav Upadhyay; Kevin Vernooy; Allan Welter-Frost; Zachary Whinnett; Francesco Zanon; Kenneth A Ellenbogen

doi:10.1016/j.jacep.2023.06.005

Cardiac Conduction System Pacing: A Comprehensive Update

JACC Clin Electrophysiol. 2023 Nov;9(11):2358-2387. doi: 10.1016/j.jacep.2023.06.005. Epub 2023 Aug 16.

Authors

Pugazhendhi Vijayaraman¹, Mihal G Chelu², Karol Curila³, Gopi Dandamudi⁴, Bengt Herweg⁵, Shumpei Mori⁶, Marek Jastrzebski⁷, Parikshit S Sharma⁸, Kalyanam Shivkumar⁶, Roderick Tung⁹, Gaurav Upadhyay¹⁰, Kevin Vernooy¹¹, Allan Welter-Frost¹², Zachary Whinnett¹³, Francesco Zanon¹⁴, Kenneth A Ellenbogen¹⁵

Affiliations

¹ Geisinger Heart Institute, Geisinger Commonwealth School of Medicine, Wilkes-Barre, Pennsylvania, USA. Electronic address: pvijayaraman1@geisinger.edu.
² Division of Cardiology, Baylor College of Medicine and Baylor St. Luke's Medical Center and Texas Heart Institute, Houston, Texas, USA.
³ Cardiocenter, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague, Czech Republic.
⁴ Virginia Mason Franciscan Health, Seattle, Washington, USA.
⁵ University of South Florida Morsani College of Medicine, Department of Cardiovascular Sciences, Tampa, Florida, USA.
⁶ University of California Los Angeles (UCLA) Cardiac Arrhythmia Center, UCLA Health System, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
⁷ First Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University, Medical College, Krakow, Poland.
⁸ Department of Cardiology, Rush University School of Medicine, Chicago, Illinois, USA.
⁹ Division of Cardiology, University of Arizona College of Medicine-Phoenix, Banner-University Medical Center, Phoenix, Arizona, USA.
¹⁰ Department of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
¹¹ Center for Arrhythmia Care, Heart and Vascular Center, University of Chicago, Chicago, Illinois, USA.
¹² Cleveland Clinic Indian River Hospital, Heart Vascular and Thoracic Institute, Vero Beach, Florida, USA.
¹³ National Heart and Lung Institute, Imperial College, London, United Kingdom.
¹⁴ Santa Maria della Misericordia Hospital, Rovigo, Italy.
¹⁵ Division of Cardiology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.

PMID: 37589646
DOI: 10.1016/j.jacep.2023.06.005

Abstract

The field of cardiac pacing has changed rapidly in the last several years. Since the initial description of His bundle pacing targeting the conduction system, recent advances in pacing the left bundle branch and its fascicles have evolved. The field and investigators' knowledge of conduction system pacing including relevant anatomy and physiology has advanced significantly. The aim of this review is to provide a comprehensive update on recent advances in conduction system pacing.

Keywords: His bundle pacing; cardiac resynchronization therapy; clinical trials; conduction system pacing; left bundle branch pacing.

Publication types

Review
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Bundle of His*
Bundle-Branch Block / therapy
Cardiac Conduction System Disease / therapy
Cardiac Resynchronization Therapy*
Electrocardiography
Heart Conduction System
Humans

Grants and funding

OT2 OD023848/OD/NIH HHS/United States