Differential Response to Interleukin-1 Blockade With Anakinra on Cardiorespiratory Fitness in Patients With Heart Failure With Preserved Ejection Fraction Stratified According to Left Ventricular Ejection Fraction

J Am Heart Assoc. 2023 Sep 19;12(18):e031251. doi: 10.1161/JAHA.123.031251. Epub 2023 Sep 18.

Michele Golino^{1

2}, Francesco Moroni^{3

4}, Salvatore Carbone^{1

5}, Giuliana Corna¹, Cory Trankle¹, Hayley E Billingsley^{1

5}, Marco G Del Buono⁶, Azita H Talasaz⁷, Georgia K Thomas¹, Roberto De Ponti², Jeremy Turlington¹, Roshanak Markley¹, Ross Arena⁸, Justin M Canada¹, Benjamin Van Tassell^{1

7}, Antonio Abbate⁹

¹ Pauley Heart Center Virginia Commonwealth University Richmond VA.
² Department of Medicine and Surgery University of Insubria Varese Italy.
³ Department of Internal Medicine University of Virginia Charlottesville VA.
⁴ Department of Medicine Università Milano-Bicocca Milan Italy.
⁵ Department of Kinesiology and Health Sciences, College of Humanities and Sciences Virginia Commonwealth University Richmond VA.
⁶ Department of Cardiovascular Medicine Fondazione Policlinico Universitario A. Gemelli IRCCS Rome Italy.
⁷ Department of Pharmacotherapy and Outcomes Sciences Virginia Commonwealth University Richmond VA.
⁸ Department of Physical Therapy, College of Applied Health Sciences University of Illinois at Chicago Chicago IL.
⁹ Robert M. Berne Cardiovascular Research Center, and Division of Cardiology University of Virginia Charlottesville VA.

No abstract available

Keywords: anakinra; cardiopulmonary exercise test; diastolic; heart failure; interleukin‐1.

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