1 Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, Sydney Street, London SW3 6NP, UK.
2 Department of Clinical and Experimental Medicine, University of Messina, 98165 Messina, Italy.
3 School of Biomedical Engineering and Imaging Sciences, Faculty of Life Sciences and Medicine, King's College University, Strand, London WC2R 2LS, UK.