Cardioprotective and Anti-Inflammatory Effects of FAM3D in Myocardial Ischemia-Reperfusion Injury

James Rhee; Rebecca Freeman; Kangsan Roh; Margaret Lyons; Chunyang Xiao; Daniel Zlotoff; Ashish Yeri; Haobo Li; Justin Guerra; J Sawalla Guseh; Alexandra Kuznetsov; Nicholas Houstis; Jason Roh; Federico Damilano; Xiaojun Liu; Michael Silverman; Raymond Kwong; Saumya Das; Anthony Rosenzweig

doi:10.1161/CIRCRESAHA.123.322640

Cardioprotective and Anti-Inflammatory Effects of FAM3D in Myocardial Ischemia-Reperfusion Injury

Circ Res. 2023 Sep 15;133(7):651-653. doi: 10.1161/CIRCRESAHA.123.322640. Epub 2023 Aug 28.

Authors

James Rhee^{1

2}, Rebecca Freeman^{1

2}, Kangsan Roh^{1

2}, Margaret Lyons^{1

2}, Chunyang Xiao¹, Daniel Zlotoff¹, Ashish Yeri¹, Haobo Li¹, Justin Guerra^{1

3}, J Sawalla Guseh¹, Alexandra Kuznetsov¹, Nicholas Houstis¹, Jason Roh¹, Federico Damilano¹, Xiaojun Liu¹, Michael Silverman¹, Raymond Kwong⁴, Saumya Das¹, Anthony Rosenzweig^{1

3}

Affiliations

¹ Department of Medicine, Cardiovascular Research Center and Division of Cardiology (J. Rhee, R.F., K.R., M.L., C.X., D.Z., A.Y., H.L., J.G., J.S.G., A.K., N.H., J. Roh, F.D., X.L., M.S., S.D., A.R.), Massachusetts General Hospital, Boston.
² Department of Anesthesia, Critical Care, and Pain Medicine (J. Rhee, R.F., K.R., M.L.), Massachusetts General Hospital, Boston.
³ Institute for Heart and Brain Health, University of Michigan Medical Center, Ann Arbor (J.G., A.R.).
⁴ Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (R.K.).

PMID: 37638415
PMCID: PMC10530060 (available on 2024-09-15)
DOI: 10.1161/CIRCRESAHA.123.322640

No abstract available

Keywords: formyl peptide receptor; heart attack; heart failure; inflammation; ischemia-reperfusion injury; myocardial infarction; ventricular remodeling.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Inflammatory Agents / pharmacology
Anti-Inflammatory Agents / therapeutic use
Cytokines
Humans
Myocardial Reperfusion Injury* / prevention & control

Substances

Anti-Inflammatory Agents
FAM3D protein, human
Cytokines

Publication types

MeSH terms

Substances

Grants and funding