Stir Fry with a Side of Extracorporeal Membrane Oxygen: Management of Cardiogenic Shock Secondary to Unintentional Aconitine Ingestion

Wilderness Environ Med. 2023 Dec;34(4):567-570. doi: 10.1016/j.wem.2023.09.006. Epub 2023 Nov 3.

Abstract

Plant exposures leading to systemic or topical toxicity are common presentations seen in the emergency department. While often nonfatal, certain highly toxic plants result in cardiovascular or respiratory failure requiring invasive management. We describe a 65-y-old patient who presented with a refractory ventricular dysrhythmia secondary to an unintentional ingestion of an aconitine-containing plant after incorrect identification. Despite aggressive treatment with vasopressors, intravenous fluids, antiarrhythmics, as well as electrolyte correction and multiple attempted synchronized cardioversions, the patient remained in a refractory dysrhythmia with cardiogenic shock. Venoarterial extracorporeal membrane oxygen (ECMO) therapy was initiated successfully and resulted in rapid resolution of the unstable dysrhythmia. The patient was weaned from ECMO in under 48 h and was discharged without neurological or cardiovascular sequelae. This case highlights management options available to clinicians who encounter toxicity associated with aconitine ingestion. Fatal consequences were averted, and caution is required with the use of plant-identifying applications and resources.

Keywords: aconite; aconitum; cardiac dysrhythmia; plants; ventricular tachycardia.

Publication types

  • Case Reports

MeSH terms

  • Aconitine*
  • Arrhythmias, Cardiac / chemically induced
  • Arrhythmias, Cardiac / therapy
  • Eating
  • Humans
  • Oxygen
  • Shock, Cardiogenic* / chemically induced
  • Shock, Cardiogenic* / therapy

Substances

  • Aconitine
  • Oxygen